Ensa Cosby – who has steadfastly supported her dad through his recent legal woes – passed away in Massachusetts.
A spokesman for the comedian asked for prayers for the Cosby family and that the family be given peace at this time.
Ensa Cosby supported her father during his sexual assault trial, saying she believed racism played a big role in the scandal.
“My father is being punished by a society that still believes black men rape white women but passes off ‘boys will be boys’ when white men are accused … the politics of our country prove my disgust. My father has been publicly lynched in the media,” she said.
Ensa Cosby appeared on one episode of The Cosby Show, which ran from 1984-1992.
Cosby lost another of his five children in 1997 when his 27-year-old son, Ennis, was shot to death while changing a flat tire near a freeway off ramp in Los Angeles.
A 22-year-old man was later convicted and sentenced to life in prison without parole.
Sexual assault retrial looms
Cosby is expected to face a retrial on April 2 on charges he drugged and molested a woman at his suburban Philadelphia home in 2004.
He has pleaded not guilty and remains free on bail.
His first sexual assault trial ended with a hung jury last June because two jurors refused to convict.
Jury selection for his retrial will start March 29.